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Meneghini LF, Hogan AR, Selvaggi G

Wherein, the phosphorylation of the C-terminus by ERK1/2 recruits -arrestins to sterically hinder interactions with GPCR kinases, initiating endocytosis likely via the assembly of clathrin-coated pits [24, 33]

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These findings are aligned with prior research, including the randomized study by Kahal et al
