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10.1001/jamanetworkopen.2023.50408 15 DaviesM

Selection is determined by side effect profiles, cost, insurance coverage, method of administration (oral vs subcutaneous), and estimated length of treatment, as some medications have only been approved for short-term use

use effective contraception if of childbearing age
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Moderate alcohol consumption is generally safe with tirzepatide, though it may exacerbate gastrointestinal side effects or increase the risk of hypoglycemia in individuals with diabetes