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24 With respect to linking reward to hedonic experience, recent evidence points to an important role for the orbitofrontal cortex (OFC), an area that receives converging sensory input

FDA has a more rapid approach for approval of chronic weight management drugs, permitting short phase 3 trials of 52 to 68 weeks without requiring pre-approval cardiovascular outcomes trials (CVOTs) whereas Europe insists on such trials

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Intestinal virome changes precede autoimmunity in type I diabetes-susceptible children

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Also, monitor for side effects like nausea, constipation, diarrhea, or bloating