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A fortnight into the first dose, things were going fine appetite down, weight ticking gently in the right direction

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General eligibility includes adults with a BMI of 30 or higher (obesity), or a BMI of 27 or higher with at least one weight-related health condition such as high blood pressure, type 2 diabetes, or high cholesterol

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The expanded MACE definition included hospitalization for heart failure, a common event in ESRD, and therefore cardiovascular findings should be interpreted descriptively rather than as evidence of benefit or harm

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