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Key Mechanism: Fiber slows digestion Reaches the colon fermented by gut bacteria Produces compounds that trigger GLP-1 release Two-Phase Effect: Immediate GLP-1 release after eating Second boost (48 hours later) Second Meal Effect Helps: Reduce cravings between meals Improve next-meal appetite control Best Fibers for GLP-1 Fermentable Fibers (Most Effective) Beta-glucans: Oats Barley Rye Seaweed Mushrooms Other Soluble Fibers Apples Pears Legumes: Lentils Chickpeas Peas 2
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(Prebiotics)
People with diabetes on semaglutide, found in Wegovy and Ozempic, four times more likely to be diagnosed with disease of optic nerve
The ever-increasing use of GLP-1 agonists is uncovering clues about what else they can do.
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