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veterans with type 2 diabetes, the WashU Medicine team found GLP-1s are tied to a reduced risk of developing substance use disorders across all major addictive substances and to a reduced risk of severe harm, including overdose and death, in people who already have such disorders

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Existing extended-release options, like weekly formulations of semaglutide and dulaglutide, have reduced injection frequency, and future innovations may include monthly formulations or implantable devices that deliver continuous therapy

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