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Notably, reductions in eGFR slope [53] and UACR [54,55] were more pronounced in people with type 2 diabetes mellitus, suggesting additional kidney-protective mechanisms beyond hemodynamic improvements and albuminuria reduction

doi:10.1001/jamaophthalmol.2025.1455 5.Prado CM, Phillips SM, Gonzalez MC, Heymsfield SB

Non-alcoholic fatty liver disease (NAFLD) is a common condition characterised by excessive fat accumulation in the liver of individuals who consume little to no alcohol (typically defined as less than 14 units per week in the UK)

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SGLT2 and SGLT2is The sodium-glucose cotransporter 2 (SGLT2) is located in the apical membrane of the S1 and S2 segments of the proximal tubule and is responsible for 90% of glucose and sodium reabsorption [83]