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Effects of glucagon-like peptide-1 receptor agonists on renal function

Keep Eating Well: Yes, your appetite might be suppressed, but your body still needs nutrients

Protein intake matters because GLP-1 medications suppress appetite so effectively that many people accidentally eat 40% or more less protein, which speeds up muscle loss

While many drugs in this class are relatively new, researchers are rapidly learning that the drugs benefits may extend well beyond managing average blood sugar levels and aiding in weight loss

Recent studies, including those carried out in the Kidney Precision Medicine Project, have shown, using single-cell RNA-Seq kidney research biopsies, the expression of the GLP-1 receptor in juxtaglomerular cells, endothelial cells, and, to a lesser extent, monocytes ( In CKD there is increased interest in the relative roles of local intrarenal macrophages versus infiltrating macrophages from the systemic circulation in promoting renal injury

Patches marketed as GLP-1 support promise convenience and simplicity, but their claims often outpace the science