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Description
The findings advocate for urgent prospective clinical trials to delineate whether these agents confer direct oncologic benefits or principally improve cancer outcomes via modulation of metabolic health

2012 Jan;97(1):121-31 Jung MJ, Kwon SK

No dose adjustments are recommended for patients with renal impairment
human risk remains uncertain), and gallbladder issues
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Selective COX-2 inhibitors: road from success to controversy and the quest for repurposing
