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Clinically, GLP-1RAs could lead to an improvement in cognitive function, which is often found to be impaired across several conditions such as psychosis 240 and mood disorders 241 , eventually leading to an overall benefit as observed in some of the included studies (Tables 4 and 5)

Bye-Bye Inflammation & Metabolic Syndrome GLP-1: Lowers inflammation, improves cholesterol & blood pressure, and supports metabolic health

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In addition to confirm comparable efficacy to injectables, oral small molecules need to show the beneficial cardiovascular effects seen with semaglutide

[DOI] [PMC free article] [PubMed] [Google Scholar] 171.Garvey W.T., Mechanick J.I., Brett E.M., Garber A.J., Hurley D.L., Jastreboff A.M., Nadolsky K., Pessah-Pollack R., Plodkowski R., Reviewers of the AACEOCPG American Association of Clinical Endocrinologists and American College of endocrinology comprehensive clinical practice guidelines for medical care of patients with obesity

This is why GLP-1 agonist medications were originally developed to treat type 2 diabetes, a condition where your cells become resistant to insulins actions over time