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They work by mimicking a natural hormone in your body that helps control appetite, slow digestion, and regulate blood sugar levels so you feel fuller, longer and avoid energy crashes

Diabetes Technol Ther 13(11):11451154

Critical nodes in signalling pathways: Insights into insulin action

Key variants in the GLP1R gene (rs6923761) and the GIPR gene (rs1800437) affect both your endogenous GLP-1 secretion and your therapeutic response to medications like semaglutide