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So on the headline number, the new oral GLP-1 pills sit close to the injectable semaglutide, and below high-dose tirzepatide

For example, if plans receive a 50% rebate on the list price of $1,300 per month (or $15,600 per year), that could mean annual net costs per person around $7,800

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More severe complications like bowel obstruction, gastroparesis, and pancreatitis have also been reported

A patient carrying loss-of-function variants in GLP1R may benefit immediately from dual-compound GLP-Squared injections ($249/month), while those with intact GLP-1 signaling often achieve superior results with compounded semaglutide alone

See here for a detailed compounded GLP-1 guide