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In reviewing the study design, an adequate number of patients were reviewed, but it is not clear how the investigators adjusted for patient age, sex and history of depression and anxiety as noted

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The thyroid operates through a feedback loop: the pituitary gland releases thyroid-stimulating hormone (TSH), which signals the thyroid to produce hormones
[DOI] [PMC free article] [PubMed] [Google Scholar] 99.Phase 2, Multicenter, Randomized, DoubleBlind, PlaceboControlled Study to Assess Effect and Safety of 400 mg Twice a Day Oral Ladarixin in Patients With Recent Onset Type 1 Diabetes and Low Residual Cell Function at Baseline (GLADIATOR), (2020), last updated November 7, 2024, accessed October 24, 2024, 100