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Description
3,249 patients were excluded due to missing demographics, age 40 years, missing demographics, prior use of any study drug, diagnosis of type 1 DM, retinal disorders classified based on the ICD categories (DR, retinal vascular occlusion, separation of retinal layers [including all types of retinal detachment and central serous retinopathy], degeneration of retina, chorioretinal inflammations, and other retinal disorders [including retinal hemorrhage, vitreous hemorrhage, retinal edema, etc.]), history of receiving vitreoretinal interventions (intravitreal injection, laser coagulation, and vitrectomy), no baseline glycosylated hemoglobin (HbA1c), or no follow-up data in the subsequent 6 months after being prescribed the medication, were excluded from this study

The result is greater weight loss than single-action GLP-1 drugs in clinical trials the SURMOUNT-1 trial reported average weight loss of 22.5% over 72 weeks at the 15 mg dose, compared to roughly 15% for semaglutides STEP-1 trial

Compounded drugs are not FDA-approved or evaluated for safety, effectiveness, or quality by the FDA

One in 8 American adults now takes a GLP-1 drug of some kind

Keep reading to discover more, as informed by medical experts and research to date

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