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Emilys approach highlights the importance of tailoring treatments to address the unique needs of PCOS patients

DXA data from the STEP-1 and SURMOUNT-1 trials show meaningful lean mass reduction during GLP-1-driven weight loss: approximately 9.7% of total lean tissue with semaglutide in STEP-1, and 10.9% with tirzepatide in SURMOUNT-1

2024 Jan 2 [cited 29 Jan 2025

Conversely, GLP-1RAs may exert direct effects on the brain, depending on their ability to cross the bloodbrain barrier (BBB)

To this end, researchers have tested leptin analogs in combination with other medications in patients with obesity to determine if any potential benefit exists

With this knowledge, studies are being conducted to determine the effects of existing GLP-1 drugs for diabetes on the central nervous system
