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The cardiorenal effects of both GLP-1RA and SGLT-2 inhibitors can be summarized as follows: GLP-1RA have moderate benefits on MACE (major cardiovascular events), may reduce all-cause mortality and hospitalization for HF (HHF), and have a robust effect in reducing the incidence of macroalbuminuria [12]

Several agents have shown cardiovascular outcome benefits in select populations, which guides therapy selection for people with existing atherosclerotic cardiovascular disease

[DOI] [PMC free article] [PubMed] [Google Scholar] 95

So whats actually going on, and which changes are worth paying attention to

Michigan cuts off weight-loss drugs for most Medicaid patients, saving $240M

doi:10.1002/jmv.25819 176
