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Unrealised Expectations Despite progress, several anticipated 2025 milestones did not come to fruition: Regulatory progress stalled: FDAs obesity drug guidance, published in draft form in January 2025, remains unfinalised, whilst EMA has yet to update its 2016 guideline

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have been pivotal for obesity treatment, achieving 1525 % weight loss over 1224 months, but questions remain about the potential influence of concomitant losses in muscle mass

Best results are achieved alongside a healthy diet and consistent exercise

Discover how GLP-1 receptor agonists affect high blood pressure in people with type 2 diabetes

Learn how to stop taking Ozempic safely

GLP-1 drugs like semaglutide may reduce opioid addiction cravings and overdose risk, according to new research.