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In a number of studies, GLP-1R agonists such as liraglutide, exenatide and lixisenatide can reduce neuroinflammation in AD models, thereby improving cognitive dysfunction (140, 141, 144148)

For those with significant obesity, referral to a Tier 3 specialist weight-management service or, where clinically appropriate, consideration of bariatric surgery under Tier 4 criteria may be appropriate

Claims with obesity diagnosis codes are automatically rejected at the pharmacy level

Long-Term: Keep vials sealed and stored at -20C for maximum stability

Tirzepatide (Mounjaro, Zepbound) targets two, GLP-1 and GIP

By combining genetic testing, biomarker context, and compounded alternatives available now, PlexusDx patients can make informed treatment decisions without waiting for generic availability, potentially achieving metabolic improvements years sooner while reducing cumulative out-of-pocket costs