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Description
Specialised laboratory techniques like liquid chromatography-mass spectrometry can detect semaglutide if specifically requested, but these are not used in routine screening
This means the sensitivity typically begins shortly after a dose is administered or after a dose increase

Patients were required to have at least one baseline measurement of weight or HbA1c within a year before drug initiation and one follow-up measurement between 9 and 15 months after initiation
To determine whether there might be a relationship between weight loss medication use immediately before or during pregnancy and various maternal and neonatal outcomes, we compared the rates of preterm delivery, high birth weight, neonatal intensive care unit (NICU) admission, and diagnoses of failure to thrive or congenital heart defect for babies born to mothers prescribed phentermine or a GLP-1 medication in the 90 days before pregnancy or during the first trimester to those with no documented weight loss medication exposure during pregnancy

A lower ratio in people who use GLP-1 medications may point to a higher risk of developing NAION, which affects blood flow to the optic nerve

doi:10.1007/s40262-018-0668-z 20
