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Protein intake also stimulates GLP-1 secretion, with studies suggesting that higher-protein meals elicit greater incretin responses compared to carbohydrate-predominant meals

56 These trials demonstrate that although orforglipron is safe and efficacious more longitudinal research is warranted to provide deeper insights into their efficacy, safety and tolerability before their potential incorporation in the pharmacological arsenal against T2DM or obesity

doi: 10.1186/s13722-025-00618-2, 42 FriedrichsenM.BreitschaftA.TadayonS.WizertA.SkovgaardD

Market Report Scope GLP-1 Receptor Agonist Market Report Coverage Uncover macros and micros vetted on 75+ parameters: Get instant access to report GLP-1 Receptor Agonist Industry News In July 2025, PolyPid Ltd
Goldstone, A

[DOI] [PMC free article] [PubMed] [Google Scholar] 84.Zhang L., et al
