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Description
Why Side Effects Happen (Simple Explanation) GLP-1 drugs mimic natural hormones that: Slow digestion Reduce hunger signals Stabilize blood sugar This combination creates weight loss benefitsbut also temporary discomfort as your body adapts

P.HsiaS.EydeS.LiuR.MaX.KonigM.et al (2023)

Is there a specific intracellular signalling pathway that mediates GLP1 agonistinduced nausea
However, the pharmacodynamics of GLP-1RAs reveal additional complexity

In one study, patients with type 1 diabetes presented with worse symptoms and were more frequently hospitalized with less resolution of symptoms than those with type 2 diabetics [32]

doi: 10.2337/dc16-0691 29 DaviesMJBergenstalRBodeBKushnerRFLewinASkjthTVet al