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A study of more than 600,000 veterans followed for up to three years found that those who started taking a GLP-1 drug for diabetes were about 15% to 20% less likely to misuse substances ranging from alcohol to opioids
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Acid contact time with the esophageal lining increases dramatically, raising the risk of esophagitis, stricture formation, and potentially Barrett esophagus with chronic exposure
Thus, formulary designers usually do not simply place GLP-1s on open coverage
