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Conclusions These data demonstrate for the first time the potent effect of semaglutide in reducing voluntary alcohol intake in non-human primates and further substantiate the need for clinical trials investigating the effect of semaglutide in patients with alcohol-use disorder.

Semaglutide was effective in lowering the concentration of low density lipoprotein (0.16 mmol/L (0.30 to 0.02)) and total cholesterol (0.48 mmol/L (0.84 to 0.11))

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As such, there is growing interest in repurposing medications with novel mechanisms of action