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Finally, the exclusion of highrisk populations introduces selection bias, and the likelihood of publication bias, whereby studies reporting favourable outcomes are overrepresented, further constrains the interpretability and clinical applicability of the existing literature

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Levothyroxine is a synthetic form of thyroxine (T4) that restores normal thyroid hormone levels, regulating metabolism, energy production, and numerous physiological processes

Patients who have tried structured diet programs, fitness interventions, or behavioral modification without sustained results become stronger candidates, as this history shows commitment and reveals biological resistance to traditional approaches

Allelic variant in the glucagon-like peptide 1 receptor gene associated with greater effect of liraglutide and exenatide on gastric emptying: A pilot pharmacogenetics study

GLP-1Rs are not only widely expressed in the central nervous system but also in peripheral nerves such as vagal afferents