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24 A reduction in the risk of dementia (HR = 0.89) among patients treated with GLP-1 medicines was also observed in a Danish registry of 120,054 patients across a 7.4-year median follow-up period

These side effects are typically mild to moderate in severity and tend to improve over time

A., & Roth, B

These data indicate that Ex-4 depresses both excitatory and inhibitory neurotransmission to cardiac vagal neurons
Similar patterns are expected with tirzepatide and retatrutide, though long-term discontinuation data for retatrutide is not yet available
and presentation should still be thoughtfully crafted
