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[1] Baseline Cardiovascular Profile The SELECT study is a large cardiovascular outcomes trial designed to assess whether semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1RA), can reduce cardiovascular events in people who are overweight or obese but do not have diabetes

2020;141:e779e806

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High BMI led to 4 million deaths worldwide in 2015, with heart disease behind two-thirds of these deaths

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