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This was not a placebo comparison

What the evidence says The most relevant published evidence focuses on paracetamol

[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Zhang T, Ruan HZ, Wang YC, Shao YQ, Zhou W, Weng SJ, et al

In particular, leptin promotes the proliferation and migration of neoplastic cells
In contrast, our results showed that individuals treated with or initiating insulin not only had higher persistence than the other groups but also showed higher treatment adherence

doi: 10.1001/jama.2018.14433
