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The pathophysiology involves dopaminergic dysfunction in the central nervous system and iron metabolism abnormalities in the brain

10.3803/ENM.2015.30.2.117 41 LeeJ

Elimination half-lives were adapted from a 2021 review paper by Nauck et al

Your doctor may change your dose as needed

EurekAlert!+2ASMBS+2 Importantly, when weighing short-term risks against long-term gainsespecially for patients with severe obesity and metabolic diseasethe costbenefit markedly favors surgery

the medication is otherwise the same
