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The competitive binding of nicotine to nicotinic cholinergic receptors induces a rapid transient allosteric conformational change to form a selective ionic channel

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Introduction Bacterial vaginosis (BV) is the most common cause of vaginitis among reproductive aged women, commonly presenting with vaginal discharge and odor ( Lactobacillus, a healthy vaginal bacteria ( Gardnerella vaginalis, Atopobium vaginae, Megasphaera spp., Prevotella spp