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If further research confirms semaglutides anti-inflammatory and neuroprotective benefits , it could mark a major breakthrough in Alzheimers treatment

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Active, not recruiting Obesity Type 2 Diabetes Drug: Tirzepatide Drug: Placebo A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity (TRIUMPH-5) The main purpose of this study is to evaluate the efficacy and safety of retatrutide compared to tirzepatide in adults who have obesity

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A letter to the editor to the Lin et al study noted the different definitions of DR progression used as the primary outcome between their study and the original CVOT studies

Less common but more serious risks include pancreatitis, gallbladder issues, and a warning (based on animal studies) about thyroid C-cell tumors