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You should arrange to see your GP if: This is your first episode of suspected thrush diagnosis should be confirmed before initiating treatment, as other conditions (bacterial vaginosis, sexually transmitted infections, dermatological conditions) can produce similar symptoms You experience recurrent infections (four or more episodes within 12 months) this may indicate an underlying condition such as diabetes or immunosuppression requiring investigation [21] [22] You are under 16 years of age these cases require assessment by a healthcare professional You are pregnant seek advice from your GP, midwife or pharmacist
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DPP-4 is a type II transmembrane glycoprotein (766 residues), involved in numerous signaling pathways (e.g., cellcell interaction and activation of transduction pathways of intracellular signals), although, under some stimuli (e.g., tumor necrosis factor (TNF) and chronic low-grade inflammation), this molecule can be released in the blood as a soluble form (sDPP-4, a protein of 727 amino acids) [45,46]

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