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Starting in 2026, one to two GLP-1RA drug launches are expected annually, with the first oral version likely debuting by 2027

doi:10.1111/j.1476-5381.2011.01369.x 93

The food intake-suppressive effects of glucagon-like peptide-1 receptor signaling in the ventral tegmental area are mediated by AMPA/kainate receptors

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When appetite is very low, focus on protein-dense, small-volume options: a protein shake, hard-boiled egg with a few bites of toast, Greek yogurt cup, or a small breakfast sandwich
