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Akkermansia muciniphila produces P9, a small protein that interacts with intercellular adhesion molecule 2 to increase thermogenesis and glucagon-like peptide-1 secretion in mice.

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This process preserves the full molecular spectrum of saffron, including volatile compounds like safranal, which are often lost during conventional extraction methods.Its content is 10 times higher in safranal and 20 times more concentrated in crocins than standard extracts, enhancing the effects of saffron on emotional balance

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