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doi: 10.1111/dom.12651

Lancet 372, 12401250

Orforglipron is currently in clinical trials and Eli Lilly is requesting a voucher from the FDA to speed up review of the pill, the officials noted

Trimi's compounded semaglutide uses the same active pharmaceutical ingredient but is prepared per individual prescription by a 503A compounding pharmacy and isn't reviewed by the FDA for safety, effectiveness, or quality before marketing

Once-daily dosing can leave gaps in coverage particularly in patients with fluctuating blood pressure or evening symptoms