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Supply chain disruptions Periodic shortages have affected tirzepatide availability, forcing involuntary treatment interruptions
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10.1056/NEJMoa1307684 64

A systematic review and meta-analysis of overweight and obese patients showed modest weight loss of 510% led to reduction in LDL-C of 0.20 mmol/dL (8 mg/dL) and triglycerides by 0.13 mmol (12 mg/dL) as well as substantial reduction in blood pressure, fasting plasma glucose, and hemoglobin A1c [26]

These advancements suggest that in the next few years, losing 25-30% of body weight with medication could become fairly routine

Maintaining results depends largely on the habits built during treatment, nutrition, activity, and muscle preservation
