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Several studies revealed that peripheral hormones, ghrelin or leptin, affect food intake through actions on the LH orexin or neurotensin neurons

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As future amino acid-based treatments seem to depend on identifying potent ligands to promote endogenous GLP-1 secretion in humans, and as the effects of oral amino acid supplementation on GLP-1 secretion in humans have been variable [44, 47,48,49], the effect of the individual amino acids on GLP-1 secretion in humans warrants further clarification

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Each comes with its own dosing curve, and researchers who have worked through one titration protocol will find the structure familiar when they approach another
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