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On the other hand, much evidence from large retrospective cohorts with endoscopic evaluation of gastric content has proven the association between incretin-based therapy exposure and increased retained gastric content [21]

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The Therapeutic Goods Administration, an arm of the Australian government, said the Trulicity shortage is expected to continue until June 30, 2026

As incretin therapies are relatively costly, cost-effectiveness studies will need to demonstrate in which high-risk population the use of incretins should be prioritized, especially in those without diabetes, where data remain scant