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By Michael S

Trump's weight loss drug announcement raises questions from the commercial market to Medicare.

Unrealised Expectations Despite progress, several anticipated 2025 milestones did not come to fruition: Regulatory progress stalled: FDAs obesity drug guidance, published in draft form in January 2025, remains unfinalised, whilst EMA has yet to update its 2016 guideline

These benefits span multiple biological systems including the nervous, musculoskeletal and respiratory systems

Unlike FDA-approved medications (e.g., Wegovy, Ozempic, Zepbound), compounded alternatives lack agency review for safety, quality, and efficacy

People using these medicines can lose more weight than with diet and exercise alone a loss of between 5% and 21% of their body weight can be expected depending on which medicine is taken and how long it is used