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Description
The normal structure and function of the intestinal barrier depend on the tight junction proteins

GLP-1 agonists, particularly tirzepatide, also cause minor increases in heart rate during the titration phase

World Obesity strongly supports WHOs message that pharmacological therapy should be implemented only as part of a comprehensive chronic care model that recognises obesity as a complex, lifelong disease

The investigators pre-select what is referred to as a primary outcome
These GLP-1 receptor agonists offer impressive health benefits, from better blood sugar control to significant weight reduction

doi: 10.1038/oby.2008.35
