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Yerba mate contains compounds that may modestly influence metabolic pathways, but research shows prescription GLP-1 medications produce far greater effects on appetite suppression and weight loss than herbal beverages alone

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Participants with diabetes treated with semaglutide did not show restored motivation

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ClinicalTrials.gov identifiers NCT01572753, NCT01619345, NCT02014259, NCT02016911, NCT02249871, NCT02172313, NCT02877355.