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What to Read Next Fatigue is also a common side effect of GLP-1s, which may be your body's clever way of conserving energy

This is remarkable progress given the historical trends with previous anti-obesity medications used (i.e., Phentermine, Low Dose Naltrexone, Orlistat, etc.) were only noted to produce an average of 3-7% total percentage of body weight lost

What It Is GLP-1 (short for glucagon-like peptide-1) is a hormone that your body makes naturally

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This can make it more difficult to maintain stable levels through diet alone

Exercise studies in healthy young men showed that skeletal muscle MOTS-c levels increase nearly 12-fold after acute exercise, suggesting this peptide mediates some of the metabolic benefits of physical activity
