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156 Mitophagy, 157 mitochondrial dynamics, 158 and mitochondrial biogenesis 158 are also affected in patients with AD, ultimately resulting in the accumulation of dysfunctional mitochondria and mitochondrial fragmentation

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The most common side effectsnausea, vomiting, and gastrointestinal discomfortoccur in 2040% of users, whereas headache reports fall significantly lower