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October 6, 2025

Hemoglobin A1c levels tend to rise within weeks to months after discontinuation, returning toward pre-treatment values
Multiple studies demonstrate beneficial effects on food cravings and disordered eating
doi: 10.1007/s40618-021-01635-z 35 AgarwalRFilippatosGPittBAnkerSDRossingPJosephAet al

However, when adverse effects such as hypoglycemia and weight gain were taken into account, sitagliptin was better tolerated

This is exactly why this conversation belongs in a rheumatologists office