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Furthermore, leptin receptor-deficient mice, a mouse model of obesity and diabetes, and people with endogenous glucagon deficiency (pancreatectomised individuals) treated with glucagon antisense oligonucleotide have increased hepatic fat [52, 53]
O impacto do fim de patentes e a entrada de genricos Nos prximos anos, um fator pode transformar ainda mais o mercado de GLP-1: o fim de patentes de algumas molculas
Acta Diabetol 2020;57:68996.ArticlePubMedPDF 7
Endocrinology 142:42444250 Dakin CL, Small CJ, Park AJ, Seth A, Ghatei MA, Bloom SR (2002) Repeated ICV administration of oxyntomodulin causes a greater reduction in body weight gain than in pair-fed rats
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