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Paik and her team analyzed data from more than 716,000 adults with type 2 diabetes who had started taking either an SGLT2 inhibitor or two other classes of diabetes medications glucagon-like peptide-1 receptor (GLP1 receptor) agonists and Upon analysis, scientists found that people who began taking SGLT2 inhibitors had a 31% decreased risk of developing kidney stones compared to those taking GLP1-receptor agonists and a 25% lower risk than people taking DPP4 inhibitors

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however, these trials were discontinued due to lack of efficacy [16]

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Immunofluorescence staining of colonic sections of DSS mice showed a noticeable decrease in DRA protein levels on the apical membrane (Figure 5)

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It is unknown whether Zepbound causes thyroid C-cell tumors, including MTC, in humans

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Mounjaro is the newest advancement in GLP-1 therapies, combining GLP-1 and GIP receptor agonists for increased weight loss effects all while minimizing side effects

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