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The observations that GLP-1 receptor agonists exert anti-inflammatory actions in preclinical studies, taken together with case reports linking improvements in psoriasis with GLP-1 receptor agonist therapy, illustrates the emerging clinical implications of non-classical anti-inflammatory actions of incretin-based therapeutics.

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Resistant fiber and starches pass through the small intestine and reach the large intestine where they are fermented by gut bacteria nourishing beneficial bacteria and promoting microbial diversity while insoluble fibers add bulk to stool