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The most recent International Diabetes Federation (IDF) report estimates that 425 million adults worldwide (8.8% of the global population) have diabetesa number that is projected to increase to 629 million by 2045 [6]

A further limitation is that reasons for discontinuation could not be assessed because of the retrospective nature of this study
True migraines, the kind with throbbing pain and neurological symptoms, were much less common

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The Na + -free bath solution contained (mmol/l): 148.4 NMDG, 4.4 KHCO 3 , 1.2 KH 2 PO 4 , 2.6 CaCl 2 , 1.2 MgCl 2 , 10 HEPES (pH 7.4 with HCl)