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[DOI] [PubMed] [Google Scholar] 4.Campbell J.N., Meyer R.A

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The structural alteration included cristae loss, membrane rupture, and mitochondrial swelling, which were observed together with an increase in ATP and a decrease in the respiration function

Monitoring and Labs for Kidney Protection Routine labs ensure efficacy and safety: Urine ACR: At least annually, or more often if elevated eGFR: Baseline and periodic monitoring Electrolytes and BP: Especially after starting SGLT2 therapy HbA1c: To assess overall glycemic trends An early dip in eGFR after starting SGLT2 inhibitors is expected and often transient