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Description
Dextroamphetamine, the active chemical for Vyvanse, has a half-life of roughly 12 hours

You're likely losing water weight and experiencing metabolic shifts that don't yet register on the scale

The result is the prolonged fullness patients describe as feeling "the meal in their chest" hours later, often accompanied by reflux as stomach contents back up against a relaxed lower oesophageal sphincter

With the end of insurance coverage, people who have spent decades trying to lose weight, including by undergoing surgery to shrink their stomachs, are scrounging for ways to afford to pay out-of-pocket for GLP-1s, or exercising and counting calories in the hopes of keeping the weight off without the drugs

[DOI] [PMC free article] [PubMed] [Google Scholar] 501.Irie S., Matsumura Y., Zdravkovic M., Jacobsen L.V., Kageyama S

on the other hand, GLP-1 analog exendin-4 could modulate these inflammatory conditions by affecting smooth muscles cytokine and chemokine expression
