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For this new approach to be considered superior, it must demonstrate similar effectiveness in controlling binge eating and associated psychopathology while also achieving clinically meaningful and sustainable weight loss over time

Although the Medicaid component of the BALANCE Model will launch May 1, the deadline for the state Medicaid agency Request for Applications (RFA) is July 31, 2026

Importantly, this includes people who have both Medicaid and Medicare, known as dual eligibles

Additionally, patients taking oral semaglutide also showed improvements in multiple cardiovascular metabolic risk factors

The retatrutide versus semaglutide comparison highlights just how much more aggressive the weight loss trajectory may be, which could have implications for how aggressively providers prescribe to patients at lower BMI ranges

NEFA, Non-esterified fatty acids